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Dukoral®

Vaccines

What DUKORAL® is used for?
  • DUKORAL® is a vaccine used to help prevent cholera and travellers’ diarrhoea caused by heat-labile toxin-producing enterotoxigenic Escherichia coli (ETEC).
  • Travellers’ diarrhoea can have many causes. ETEC is only one cause.DUKORAL® will only prevent travellers’ diarrhoea due to ETEC. DUKORAL® is used to protect people who are travelling to an area where there is a risk of cholera or diarrhoea due to ETEC.
  • DUKORAL® can be used in children >2 years and in adults.

How it works
  • DUKORAL® works by causing your body to produce its own protection against cholera and ETEC diarrhoea. It does this by making substances called antibodies in the intestine wall, which fight the cholera bacteria (Vibrio cholerae) and the cholera toxin. Cholera toxin causes diarrhoea and is produced by the cholera bacteria. ETEC produces a toxin, which is almost identical to the cholera toxin, and the antibodies also protect against this toxin.
  • If a vaccinated person comes into contact with cholera bacteria or cholera toxin, the body is usually ready to destroy it.
  • Your body usually takes two weeks after vaccination to develop protection against diarrhoea due to cholera or ETEC.
  • Most people will produce enough antibodies to protect against diarrhoea due to cholera or ETEC. However, as with all vaccines, 100% protection cannot be guaranteed.

How to take DUKORAL®
Cholera:
the course of primary vaccination is:
  • 2 doses for adults and children over the age of 6.
  • Children from 2 to 6 years of age should receive three doses.
  • Doses are to be administered with an interval of 1 to 6 weeks between them.
  • Adults and children over 6 years should receive a booster dose after 2 years and children 2–6 years should receive a booster dose after 6 months. 

ETEC:
the course of primary vaccination for adults and children is:
  • 2 doses with an interval of 1 to 6 weeks between doses.

DUKORAL® comes in the form of a single sachet per dose that is dissolved in water.

When to take it
Avoid food and drink 1 hour after vaccination.
DUKORAL® sachets must be stored in the fridge (between 2°C and 8°C)

Note.  Information on this site is not intended to replace the advice given by your doctor or health professional.

     

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Last Updated: 16-09-2013
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